Response to Zambon et al.

نویسندگان

  • Caroline Laplante
  • Thomas D. Pollard
چکیده

Stimulated by our 2015 Current Biology paper [1], Zambon et al. reinvestigated how three myosin isoforms participate in the formation and constriction of the contractile ring in fission yeast. Our paper presented evidence that these myosin isoforms have distinct roles: "Conventional myosin-II Myo2 is crucial to ring assembly, unconventional myosin-II Myp2 is most important for ring constriction, and type V myosin Myo51 aids the other two myosins." Zambon et al. used different markers to reexamine the contributions of the three myosins to cytokinesis and concluded "that Myo2p is the major motor involved in ring contraction in S. pombe." Here, we show that most of the differences observed by Zambon et al. can be attributed to their use of the Rlc1p-3GFP marker, which genetically interacts with myo2-E1.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Impact of Bacteria-Induced Adaptive Immune Responses in Periodontal Disease

More than one microorganism causes periodontal disease, like many infectious diseases in humans. Because of the complexity of “polymicrobial infections”, their study requires a multidisciplinary approach, employing specific in vitro techniques, and various animal models (Bakaletz 2004). Inherently, no one approach or animal model can completely elucidate the mechanisms of periodontal disease. N...

متن کامل

Assesment of different DNA extraction methods in medicinal plants

Medicinal plants have high importance in medicine and pharmacogonosy because of their secondary metabolites. Essential oils, antioxidants and flavonoids are the major compounds of many medicinal plants. These compounds especially antioxidants can increase oxidation of DNA in response to wounds. Nowadays, progresses in biotechnology such as molecular markers were used for phylogenetic relationsh...

متن کامل

Assesment of different DNA extraction methods in medicinal plants

Medicinal plants have high importance in medicine and pharmacogonosy because of their secondary metabolites. Essential oils, antioxidants and flavonoids are the major compounds of many medicinal plants. These compounds especially antioxidants can increase oxidation of DNA in response to wounds. Nowadays, progresses in biotechnology such as molecular markers were used for phylogenetic relationsh...

متن کامل

Stopping a medical research project for financial reasons.

Letters Stopping a medical research project for financial reasons Sir, We are writing to provide some clarifications on the Editorial Comment by Druëke et al. [1]. We would have been happy to provide these very same clarifications had we been fairly invited to do so before the publication of the article. First of all, we would like to underline that cancelling a clinical trial is always a diffi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Current Biology

دوره 27  شماره 

صفحات  -

تاریخ انتشار 2017